158798-83-5

AK 275 is an inhibitor of calpain that prevents degradation of cytoskeletal and myelin proteins in spinal cord in vitro.

AK 275, a calpain inhibitor, exhibits neuroprotection activity. AK 275 can be used in the study for central nervous system trauma and ischemia[1].

[1] T James, et al. New inhibitors of calpain prevent degradation of cytoskeletal and myelin proteins in spinal cord in vitro. J Neurosci Res. 1998 Jan 15;51(2):218-22. DOI:10.1002/(SICI)1097-4547(19980115)51:2<218::AID-JNR10>3.0.CO;2-4