156907-84-5

OSU 6162 Hydrochloride is a weak dopamine D2 receptor antagonist. It is a salt analogue of (-)-OSU (O006162).

Dopamine stabilizer that lacks high in vitro affinity for various neuroreceptors (K i values are 447 and 1305 nM for D 2 and D 3 receptors respectively and > 1 μ M for other targets). In vivo, shows high D 2 receptor occupancy and is highly active on dopamine synthesis and turnover. Induces stabilizing effects on psychomotor function in behavioral tests without inducing hypolocomotion or catalepsy.

Store at +4°C