155058-71-2

SM-21 is a potent and selective σ2 antagonist, increasing release of ACh.

ChEBI: 2-(4-chlorophenoxy)butanoic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester is a monocarboxylic acid.

Potent and selective σ 2 antagonist with central effects following systemic administration. Causes increased release of acetylcholine at central muscarinic synapses. Potent analgesic (efficacy comparable to morphine) and nootropic agent.