150608-41-6

CGP 57813 is a lipophilic compound that acts as a inhibitor of human immunodeficiency virus type 1 (HIV-1) protease.

CGP 57813 is a peptidomimetic inhibitor of HIV protease that can be encapsulated by nanoparticles composed of poly(D,L-lactic acid) (PLA) and pH-sensitive methacrylic acid copolymers and delivered into the body[1].

[1] Leroux JC, et al. Pharmacokinetics of a novel HIV-1 protease inhibitor incorporated into biodegradable or enteric nanoparticles following intravenous and oral administration to mice. J Pharm Sci. 1995 Dec;84(12):1387-91. DOI:10.1002/jps.2600841202