ChemicalBook CAS DataBase List 150566-71-5

150566-71-5

Name	S-Amlodipine
CAS	150566-71-5
Molecular Formula	C26H31ClN2O8S
MDL Number	MFCD07773085
Molecular Weight	567.051
MOL File	150566-71-5.mol

Chemical Properties

storage temp.	-20°C, protect from light
solubility	DMSO : ≥ 150 mg/mL (264.53 mM)
form	Solid
color	White to light yellow
InChIKey	ZPBWCRDSRKPIDG-VOPAOICTNA-N
SMILES	O=S(=O)(O)C1=CC=CC=C1.O=C(OCC)C1[C@@H](C2=C(Cl)C=CC=C2)C(C(=O)OC)=C(C)NC=1COCCN \|&1:16,r\|

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Shengyang Runze (Beijing) Technology Co.,

Telephone 17611011830

Websitehttps://www.syrz01.com

Nanjing Sunlida Biological Technology Co., Ltd.

Telephone025-57798810 18652991625

Website

ShangHai Caerulum Pharma Discovery Co., Ltd.

Telephone18149758185 18149758185

Websitehttp://www.caerulumpharma.com

Bide Pharmatech Ltd.

Telephone400-164-7117 18317119277

Websitehttp://www.bidepharm.com

Shanghai YuanYe Biotechnology Co., Ltd.

Telephone 18916372613

Websitehttps://www.shyuanye.com

Hubei Yangxin Medical Technology Co., Ltd.

Telephone 15374522761

Websitehttps://www.standardpharm.org.cn/

Fan De(Beijing) Biotechnology Co., Ltd.

Telephone 15911056312

Websitehttp://www.bio-fount.com/

Dideu Industries Group Limited

Telephone+86-29-89586680 +86-15129568250

Websitehttps://www.dideu.com

Chengdu Peter-like Biotechnology Co., Ltd.

Telephone18108052721

Websitehttps://www.weikeqi-biotech.com/

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Telephone 18818260767

Websitehttp://www.chemegen.com

Shanghai Xinlitai Pharmaceutical Co. , Ltd.

Telephone 18616665298

Websitehttp://www.neoleading.com/

Jinan Winsor Pharmaceutical Co., Ltd

Telephone152-64160071 15318402391

Websitehttp://www.xinhechem.cn/

SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD

Telephone0755-83725350 13380397412

Websitehttps://www.sincopharmachem.net

Beijing Jin Ming Biotechnology Co., Ltd.

Telephone010-60605840

Websitehttp://www.jm-bio.com/

Bide Pharmatech Ltd.

Telephone400-1647117 13681763483

Websitehttps://www.bidepharm.com/

InvivoChem

Telephone 13549236410

Websitehttps://www.invivochem.cn/

Hubei Weideli Chemical Reagent Co.，Ltd.

Telephone186-02735115 18062128043

Websitehttps://www.chemicalbook.com/supplier/24579120/

TargetMol Chemicals Inc.

Telephone4008200310 15002144251

Websitehttps://www.targetmol.cn/

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Animal Model:	Spontaneously hypertensive rats (SHR)^[3].
Dosage:	1 mg/kg
Administration:	Oral gavage (p.o.); once daily; 16 weeks
Result:	Reduced systolic blood pressure (SBP) and diastolic blood pressure (DBP), reduced heart and aortic hypertrophy, increased kidney weight to prevent kidney atrophy.

Animal Model:	VaD mice model of right unilateral common carotid arteries occlusion (rUCCAO)^[1].
Dosage:	0.1, 0.5 mg/kg
Administration:	Oral gavage (p.o.); once daily; 8 weeks
Result:	Recovered phosphorylated CaMKII (Thr286) levels in the hippocampus and improved cognitive impairment in mice.

150566-71-5

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