150450-42-3

Potent and specific inhibitor of cGMP-specific phosphodiesterase (PDE V, IC₅₀ = 230 nM). Elevates the intracellular cGMP level without causing a change in the cAMP level in isolated porcine coronary arteries. Has no effect on other PDE isoenzymes.

ChEBI: N-(1,3-benzodioxol-5-ylmethyl)-6-methoxy-4-quinazolinamine is a member of quinazolines.

Primary Target
CGMP-PDEV