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Dimoxystrobin is mainly used as a cereal fungicide. It has a low aqueous solubility and a low volatility. It can be persistent in both soil and water systems. It is highly toxic to earthworms and fish it tends to be classified as moderate to low for other species. Dimoxystrobin has a low oral mammalian toxicity and is an endocrine disruptor.

The product is a white crystalline solid with a purity of ≥98%. Its melting point is 138.1-139.7°C and its relative density is 1.235 at 25°C. Its vapor pressure is 6×10-4 mPa at 25°C. Its partition coefficient, KowlogP, is 3.59 at pH 6.5. Its solubility in water (20°C, mg/L) is 4.3 at pH 5.7 and 3.5 at pH 8. Its solubility in organic solvents is >250 in dichloromethane, 200-250 in N,N-dimethylformamide, 67-80 in acetone, 50-57 in acetonitrile, 33-40 in ethyl acetate, 20-25 in toluene, 20-25 in methanol, and <10 in isopropanol, n-heptane, n-octanol, and olive oil. It is stable in aqueous solution at pH 4-9 and 50°C for 30 days.

Dimoxystrobin is a pesticide component used for its antifungal activity.

ChEBI: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2E)-{2-[(2,5-dimethylphenoxy)methyl]phenyl}(methoxyimino)acetic acid with the amino group of methylamine. A fungicide used for disease control in cereals, vegetables and turf.

The commercial production of dimoxystrobin involves a multi-step process. It begins with the condensation of 2,5-dimethylphenol with 2-(bromomethyl)phenylacetic acid to form an intermediate, followed by oximation with methoxyamine hydrochloride under basic conditions to introduce the methoximino group. This is coupled with N-methylamine to form the amide linkage, typically in an organic solvent like toluene, with controlled temperature to optimize yield.

Protectant, curative and translaminar. Respiration inhibitor (QoL fungicide).

Fungicide