147819-32-7

JB1 is an IGF-I peptide analog; IGF-1 receptor antagonist. IGF-1once known as somatomedin Cis involved in a multitude of activites including promoting growth and developmentparticularly neural developmentand involved in the growth and proliferation in a variety of human cancers. JB1 is a 12-amino acid cyclic peptidean IGF-1 analogused by researchers in a variety of fields to inhibit IGF activity by inhibiting binding of IGF-1 to its receptor.