145858-50-0

Name	5-[(3-CHLOROPHENYL)-1H-IMIDAZOL-1-YLMETHYL]-1H-BENZIMIDAZOLE HYDROCHLORIDE
CAS	145858-50-0
Molecular Formula	C17H14Cl2N4
MDL Number	MFCD00879803
MOL File	145858-50-0.mol

Synonyms

R75251 R-75251 R 75251 Liarozole HCl Liarozole dihydrochl LIAROZOLE HYDROCHLORIDE 5-[(3-CHLOROPHENYL)-1H-IMIDAZOL-1-YLMETHYL]-1H-BENZIMIDAZOLE HYDROCHLORIDE

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Chemical Properties

storage temp.

Store at +4°C

Hazard Information

Uses

Antineoplastic.

Uses

Liarozole Hydrochloride is a Imidazole-containing compound that inhibits the cytochrome P450-dependent metabolism.

Biological Activity

Cytochrome P450 inhibitor. Inhibits several cytochrome P450 enzymes including aromatase (CYP19) and retinoic acid 4-hydroxylase (CYP26). Blocks retinoic acid metabolism (retinoic acid metabolism blocking agent, RAMBA). Displays antitumor activity against androgen-dependent and independent rat prostate carcinomas.

Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.

Telephone821-50328103-801 18930552037

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm

Energy Chemical

Telephone021-58432009 400-005-6266

Websitehttp://www.energy-chemical.com

Shanghai Universal Biotech Co.,Ltd

Telephone 18768175414

Websitehttps://www.univ-bio.com/

TargetMol Chemicals Inc.

Telephone 4008200310

Websitehttps://www.targetmol.cn/

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