Bibn 140 is a highly selective M2 antagonist with applications to Alzheimer's disease and other cognitive disorders.
Uses
Bibn 140 is a pyridine derivative substituted with a benzene ring, which has high affinity (Ki: 12 nM) and selectivity for M2 mAChR receptors over M1 receptors[1].
References
[1] THERAPEUTIC POTENTIAL OF CNS-ACTIVE M 2 ANTAGONISTS: NOVEL STRUCTURES AND PHARMACOLOGY
