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ChemicalBook CAS DataBase List 1449373-99-2

1449373-99-2 Structure

1449373-99-2

Name	DQP-26
CAS	1449373-99-2

Synonyms

DQP-26

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Chemical Properties

form	Solid
color	White to off-white

Hazard Information

Uses

DQP-26 is a potent NMDAR negative allosteric modulator with IC50 values of 0.77 μM and 0.44 μM for GluN2C and GluN2D, respectively. DQP-26 has the potential for NMDAR-associated neurological disease research[1].

References

[1] Michael P D'Erasmo, et al. Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor. ACS Chem Neurosci. 2023 Sep 6;14(17):3059-3076. DOI:10.1021/acschemneuro.3c00181

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Shanghai Beckham Medical Technology Co., Ltd

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