1438284-00-4

Name	JAK2-IN-4
CAS	1438284-00-4
Molecular Formula	C23H27N5O4S
MDL Number	MFCD30747859
Molecular Weight	469.56
MOL File	1438284-00-4.mol

Synonyms

JAK2-IN-4 JAK2-IN-4 (COMPOUND 16H) JAK-2-IN-4,JAK2 IN 4,JAK2IN4 2-Pyrimidinamine, 5-methyl-N-[4-(4-morpholinyl)phenyl]-4-[4,5,6,7-tetrahydro-5-(methylsulfonyl)furo[3,2-c]pyridin-2-yl]-

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Chemical Properties

storage temp.	Store at -20°C
solubility	Soluble in DMSO

Hazard Information

Description

JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively[1]. IC50: 0.7 nM/23.2 nM (JAK2/JAK3)[1].

storage

Store at -20°C

References

[1]. Wang Y, et al. Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors. Bioorg Med Chem. 2017 Jan 1;25(1):75-83.

Supplier

ShangHai Caerulum Pharma Discovery Co., Ltd.

Telephone18149758185 18149758185

Websitehttp://www.caerulumpharma.com

Chengdu Peter-like Biotechnology Co., Ltd.

Telephone028-81700200 18108052721

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList111931/0.htm

TargetMol Chemicals Inc.

Telephone 4008200310

Websitehttps://www.targetmol.cn/

Suzhou Zhixin Biotechnology Co., Ltd.

Telephone0512-65118909 15162312715

Websitehttp://www.szzxbio.com/

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