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Zn(II) Mesoporphyrin IX (ZnMP) is a specific activator of ABCB10, significantly increasing its ATPase activity and acting as a substrate for ABCB10 in heme synthesis. Zn(II) Mesoporphyrin IX may promote the transcription of hemoglobinization genes by facilitating the degradation of the Bach1 repressor. Zn(II) Mesoporphyrin IX aids in studying the potential roles of ABCB10 in heme synthesis, oxidative stress protection, hepatitis C, and other areas[1][2].

[1] Martinez M, et al. Stimulation of the human mitochondrial transporter ABCB10 by zinc-mesoporphrin. PLoS One. 2020 Nov 30;15(11):e0238754. DOI:10.1371/journal.pone.0238754
[2] Clark ER, et al. Photosensitized H2 generation from "one-pot" and "two-pot" assemblies of a zinc-porphyrin/platinum nanoparticle/protein scaffold. Dalton Trans. 2016 Jan 14;45(2):630-8. DOI:10.1039/c5dt03418c