1433857-09-0

Name	Lascufloxacin hydrochloride
CAS	1433857-09-0
Molecular Formula	C21H25ClF3N3O4
Molecular Weight	475.89
MOL File	1433857-09-0.mol

Synonyms

KRP-AM1977Y Lascufloxacin HCl Lascufloxacin hydrochloride

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Hazard Information

Uses

Lascufloxacin (KRP-AM1977) hydrochloride is a potent antibacterial compound candidate with broad-spectrum activity against various clinical isolates. Lascufloxacin hydrochloride shows the most potent activity against Gram-positive bacteria compared to other tested quinolones. Lascufloxacin hydrochloride demonstrates incomplete cross-resistance against existing quinolone-resistant strains. Lascufloxacin hydrochloride has potent inhibitory activity against both wild-type and mutated target enzymes.

Biological Activity

Lascufloxacin hydrochloride has potent activity against a broad range of pathogens, including aerobic and anaerobic strains, and is able to inhibit both wild-type and mutant targets, making it effective against fluoroquinolone-resistant bacterial strains.

Synthesis

The synthesis of Lascufloxacin hydrochloride can follow the route below

References

[1] In Vitro Activities and Spectrum of the Novel Fluoroquinolone Lascufloxacin (KRP-AM1977) DOI:10.1128/AAC.00120-17

Supplier

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Hangzhou MolCore BioPharmatech Co.,Ltd.

Telephone+86-057181025280; +8617767106207

Websitehttps://www.molcore.com/

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