Description
PF-06465603 is a metabolite of PF-04691502 (MedKoo CAT#: 202226), a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR.
Uses
PF-06465603 is a highly potent and selective ATP-competitive kinase inhibitor and a class 1 PI3K and mTOR inhibitor. PF-06465603 is a metabolite of PF-04691502 with a terminal carboxylic acid structure[1].
References
[1] Structure-based design, SAR analysis and antitumor activity of PI3K/ mTOR dual inhibitors from 4-methylpyridopyrimidinone series
