1427325-40-3

JWH 018 is a synthetic cannabinoid (CB) that potently activates the central CB₁ and peripheral CB₂ receptors (K_i = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. JWH 018 N-(1,2-dimethylpropyl) isomer differs from JWH 018 structurally by having a 1,2-dimethylpropyl chain, rather than a pentyl chain, extending from the indole group. The biological activities of this compound have not been characterized. This product is intended for forensic purposes.

[1] RAINER LINDIGKEIT . Spice: A never ending story?[J]. Forensic science international, 2009, 191 1: Pages 58-63. DOI: 10.1016/j.forsciint.2009.06.008
[2] N. UCHIYAMA. Identification of a cannabimimetic indole as a designer drug in a herbal product[J]. Forensic Toxicology, 2009, 27 1: 61-66. DOI: 10.1007/s11419-009-0069-y