1426916-02-0

ML-298 is an inhibitor of phospholipase D₂ (PLD₂; IC₅₀ = 355 nM). It is selective for PLD₂ over PLD₁ (IC₅₀ = 20,000 nM). It decreases invasive migration of U87-MG glioblastoma cells when used at a concentration of 10 μM without inducing cytotoxicity.

ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2).

ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2; IC50 = 355 nM). ML298 does not affect PLD1 activity at concentrations up to 20 μM.

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