Squalestatin 2 is a potent squalene synthase inhibitor. Squalestatin 2 has IC50 values of 5 and 4 nM in rat liver and tobacco, respectively[1].
References
[1] Fulton DC, et al. Comparative study of the inhibition of rat and tobacco squalene synthase by squalestatins. Phytochemistry. 1995 Mar;38(5):1137-41. DOI:10.1016/0031-9422(94)00798-x
