1422515-55-6

((3R,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate) calcium(II) is an impurity found in bulk preparations of the HMG-CoA reductase inhibitor Rosuvastatin (HY-17504A).

(3R,5R)-Rosuvastatin is a potential impurity found in bulk preparations of the HMG-CoA reductase inhibitor rosuvastatin.1 It is a degradation product formed by acid or base hydrolysis, thermal, photolytic, hydrolytic, or oxidative stress, or during storage.

-20°C

1.Koppala, S., Rayam, P., Reddy, V.R., et al.Identification, isolation, characterization and quantification of a new impurity in rosuvastatin calcium tablet dosage formAnal. Chem. Ind. J.16(10)417-432(2016)