Chemical Properties
White to Off-White Solid
Uses
Tiletamine is a receptor antagonist, an anesthetic
Indications
Tiletamine hydrochloride/zolazepam hydrochloride is used for chemical immobilization and surgical anesthesia in a wide variety of carnivores, artiodactylids, birds, reptiles, and amphibians.
Veterinary Drugs and Treatments
Telazol? is indicated for restraint or anesthesia combined with
muscle relaxation in cats, and for restraint and minor procedures
of short duration (≈30 minutes) which require mild to moderate
analgesia in dogs. Although not officially approved, it has been used
also in horses and many exotic and wild species.
Mode of action
Tiletamine hydrochloride is a dissociative anesthetic agent whose pharmacologic action is characterized by profound analgesia, normal pharyngeal-laryngeal reflexes and cataleptoid anesthesia. Used alone, tiletamine hydrochloride does not provide adequate muscle relaxation for abdominal surgical procedures. When combined with zolazepam hydrochloride, good muscle relaxation is generally attained during the phase of deep surgical anesthesia. Tilzolan is a rapid-acting anesthetic combination of tiletamine hydrochloride and zolazepam hydrochloride.
