141443-40-5

AB023b is an antibiotic that displays antifungal properties.

Antibiotic AB023b is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023a (HY-137084). Antibiotic AB023b exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea, Fusarium moniliforme and Pythium ultimum[1][2].

[1] Bortolo R, et al., AB023, novel polyene antibiotics. II. Isolation and structure determination. J Antibiot (Tokyo). 1993 Feb;46(2):255-64. DOI:10.7164/antibiotics.46.255
[2] Cidaria D, et al., AB023, novel polyene antibiotics. I. Taxonomy of the producing organism, fermentation and antifungal activity. J Antibiot (Tokyo). 1993 Feb;46(2):251-4. DOI:10.7164/antibiotics.46.251