1402837-76-6

IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, Compound 1486, has an IC50 of <1 μM.

IDO-IN-6 (Compound 1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of <1 μM (this is the concentration of IDO-IN-6 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].

[1]. Mautino, et al. Preparation of fused imidazole derivatives as IDO inhibitors. From PCT Int. Appl. (2012), 20121018.