Biological Activity
Betulinic acid propargyl ester is a pentacyclic lupane triterpene and alkyne derivative of betulinic acid .1,2 It has been used in click chemistry reactions for the synthesis of cytotoxic anticancer betulinic acid derivatives.
References
1.Thi, T.A.D., Tuyet, N.T.K., The, C.P., et al.Synthesis and cytotoxic evaluation of novel ester-triazole-linked triterpenoid-AZT conjugatesBioorg. Med. Chem. Lett.24(22)5190-5194(2014)
2.B?benek, E., Chrobaka, E., Wietrzyk, J., et al.Synthesis, structure and cytotoxic activity of acetylenic derivatives of betulonic and betulinic acidsJ. Mol. Struct.1106210-216(2016)
