ChemicalBook CAS DataBase List 1391108-10-3

1391108-10-3

Chemical Properties

density	1.34±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO mg/mL Water mg/mL Ethanol mg/mL
pka	2.32±0.40(Predicted)

Jinan Trio PharmaTech Co., Ltd.

Telephone0531-88811783

Websitehttp://www.trio-pharmatech.com

SPIRO PHARMA

Telephone

Websitehttp://www.spiropharma.com.cn

Energy Chemical

Telephone400-0056266

Websitehttp://www.energy-chemical.com

Wuhan Yanzhe Technology Co., Ltd

Telephone 15527250409

Websitehttps://www.chemicalbook.com/Supplier/23754455/

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Telephone13611835272 13611835272

Websitehttp://www.sunwaypharm.cn/

Shanghai Yiyan Biotechnology Co. , Ltd.

Telephone021-69985186 13611928337

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList1691458/0_EN.htm

Hangzhou Bingochem Co., Ltd.

Telephone0571-87658025

Websitehttp://www.bingochem.com/

HANGZHOU LEAP CHEM CO., LTD.

Telephone+86-571-87711850 +8619957148339

Websitehttps://www.leapchem.com

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Animal Model:	SCID mice (injected with 5 x 10⁶ H146 cancer cells with Matrigel, subcutaneously)^[1]
Dosage:	15 mg/kg
Administration:	i.v., 15 mg/kg, daily, 5 days a week for 2 weeks
Result:	Showed good toleration and did not cause significant weight loss or other signs of toxicity, also induced completely and persistent tumor regression in the H146 xenograft model.

Animal Model:	SCID mice (injected with 5 x 10⁶ H146 cancer cells with Matrigel, subcutaneously)^[1]
Dosage:	15 mg/kg
Administration:	i.v., 15 mg/kg, single dosage
Result:	Induced robust cleavage of PARP and caspase-3 at both 3 and 6-hr time-points in H146 tumor tissues.