137058-21-0

Tyrosinase-IN-33 (compound 5) a Pyridine-based compound, is a potent inhibitor of mushroom tyrosinase diphenolase activity. Tyrosinase-IN-33 significantly decreases the enzyme activity, with an IC50 of 9.0 μM[1].

[1] Lotfi Shahpar E, et al. Inhibitory Effects, Fluorescence Studies, and Molecular Docking Analysis of Some Novel Pyridine-Based Compounds on Mushroom Tyrosinase. Biochemistry. 2024 Aug 20;63(16):2063-2074. DOI:10.1021/acs.biochem.4c00204