136470-65-0

Name	Banoxantrone dihydrochloride
CAS	136470-65-0
Molecular Formula	C22H28N4O6
Molecular Weight	444.48
MOL File	136470-65-0.mol

Synonyms

Banoxantrone YZBAXVICWUUHGG-UHFFFAOYSA-N Banoxantrone dihydrochloride 9,10-Anthracenedione, 1,4-bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy- 1,4-Bis{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxyanthracene-9,10-dione bis-N-oxide

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Hazard Information

Uses

Banoxantrone (AQ4N) is a hypoxia-activated prodrug of topoisomerase II inhibitor AQ4 (Bioreductive AQ4 precursor). studies have shown that its has also exhibited anti-tumor efficacy in vivo when combined with oxic cell cytotoxins.

in vivo

Banoxantrone (200 mg/kg; i.p.; single dose) significantly inhibits T50/80 tumours and induces cell damage in BDF mice^[1].

IC 50

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Supplier

Lanzhou Angeli Biochemical Technology Co., Ltd.

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Shanghai Zeye Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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Suzhou Meishi Biotechnology Co., Ltd.

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Nantong QuanYi Biotechnology Co., Ltd

Telephone0513-66337626 18051384581

Websitehttps://www.chemhifuture.com/

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