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Cyanine3 carboxylic acid belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.

[1] Armitage B A. Cyanine dye–DNA interactions: intercalation, groove binding, and aggregation[J]. DNA Binders and Related Subjects: -/-, 2005: 55-76.