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XZH-5 is a STAT3 inhibitor.

XZH-5 inhibits the phosphorylation of STAT3 and results in the induction of apoptosis and reduction of colony forming ability[1].

[1] Li Chenglong, et al. Compound XZH-5 inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human hepatocellular carcinoma cells. World Intellectual Property Organization, WO2012078982 A2 2012-06-14