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Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker[1]. Boc-Pip-butyn is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker[1].

Alkyl/ether

[1]. Yulu Zhou, et al. Photocatalytic Sulfonylcarbocyclization of Alkynes Using SEt as a Traceless Directing Group: Access to Cyclopentenes and Indenes. Angew Chem Int Ed Engl. 2022 Jan 3;61(1):e202110864.