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RuDiOBn scanvages DPPH and ABTS free radicals (13.2% and 5.9% clearance at 100 μg/mL), exhibits low antioxidant activity. RuDiOBn inhibits the collagen glycation, reduces the formation of advanced glycation end products (AGEs) with an IC50 of 2.45 μg/mL. RuDiOBn enhances the proliferation and migration of fibroblasts, stimulates the synthesis of collagen, promoting the skin repair and regeneration. RuDiOBn also inhibits collagenase[1].

[1] da Silva BJP, et al., Synthesis of a New Benzylated Derivative of Rutin and Study of Its Cosmetic Applications. ACS Omega. 2025 Feb 28;10(9):8883-8890. DOI:10.1021/acsomega.4c04908