134377-69-8

Name	Safironil
CAS	134377-69-8
Molecular Formula	C15H23N3O4
Molecular Weight	309.36
MOL File	134377-69-8.mol

Synonyms

Safironil 2,4-Pyridinedicarboxamide, N2,N4-bis(3-methoxypropyl)-

show less show more

Hazard Information

Uses

Safironil is an antifibrotic compound. Safironil is a competitive inhibitor of collagen protein synthesis. Safironil reduces liver fibrogenesis by inhibiting HSC activation[1][2].

References

[1] NO Al-Harbi, et al. Reversal of Liver Fibrosis in Chronic Murine Schistosomiasis mansoni by Safironil/Praziquantel. Tropical Journal of Pharmaceutical Research. Vol. 11 No. 4 (2012)
[2] Wang YJ, et al. Two novel antifibrotics, HOE 077 and Safironil, modulate stellate cell activation in rat liver injury: differential effects in males and females. Am J Pathol. 1998 Jan;152(1):279-87. PMID:9422545

Spectrum Detail

Safironil(134377-69-8)¹HNMR

Supplier

Jinan ponder chemical co. LTD

Telephone0531-0000

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList546697/0_EN.htm

Shanghai Yifei Biotechnology Co. , Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Shaoguan Qicheng Biotechnology Co., Ltd

Telephone 18122215013

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList1488808/0_EN.htm

Sangon Biotech (Shanghai) Co.,Ltd.

Telephone400-821-026

Websitehttp://www.sangon.com

PROMPT×

PROMPT
The What'sApp is temporarily not supported in mainland China

Cancel

Determine

Send Inquriy