Spm viii is a derivative of the nucleoside antibiotic spicamycin with antitumor activity.
Uses
SPM VIII is a dodecanoyl analogue of spicamycin, a nucleoside antibiotic that contains fatty acids of various chain lengths. SPM VIII exhibits potent antitumor activity against the human gastric cancer SC-9 xenograft model[1].
References
[1] Kamishohara M, et al. Structure-antitumor activity relationship of semi-synthetic spicamycin analogues. J Antibiot (Tokyo). 1993 Sep;46(9):1439-46. DOI:10.7164/antibiotics.46.1439
