CK 3197 is a selective positive inotropic agent for the treatment of congestive heart failure. It has hemodynamic and myocardial energetic effects.
Uses
CK-3197 is a weak inhibitor of Peak lll cyclic 3'5'-adenosine monophosphate phosphodiesterase
(CAMP PDEl). CK-3197 has hemodynamic and myocardial energetic effects in vivo. CK-3197 is an imidazolone derivative used as a selective positive inotropic agent for congestive heart failure[1].
References
[1] Greenberg S, et al. Hemodynamic and myocardial energetic effects of CK-3197, a selective positive inotropic agent. J Cardiovasc Pharmacol. 1991 Jan;17(1):145-53. DOI:10.1097/00005344-199101000-00021