132196-54-4

Chrodrimanin B is a meroterpenoid fungal metabolite with insecticidal activity against third instar silkworm larvae.

Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on?B.?mori GABAR RDL with an IC50?of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC50?of 1.66 nM.?Chrodrimanin B, a meroterpenoid, shows insecticidal activity[1].

ChEBI: Chrodrimanin B is an organic heteropentacyclic compound.

[1] Yan Xu, et al. Meroterpenoid Chrodrimanins Are Selective and Potent Blockers of Insect GABA-Gated Chloride Channels. PLoS One. 2015 Apr 22;10(4):e0122629. DOI:10.1371/journal.pone.0122629