E5090, a novel orally active inhibitor of IL-1 generation, has antiinflammatory properties.
Uses
E5090 is an orally active inhibitor of IL-1 generation which is converted in vivo into the pharmacologically active deacetylated form (DA-E5090). E5090 can be utilized in immunology research[1].
IC 50
IL-1
References
[1] Goto M, et al. A novel inhibitor of IL-1 generation, E5090: in vitro inhibitory effects on the generation of IL-1 by human monocytes. Agents Actions Suppl. 1991;32:225-9. DOI:10.1007/978-3-0348-7405-2_30
