1307803-47-9

JWH 073 is a mildly selective agonist of the central cannabinoid (CB₁) receptor derived from the aminoalkylindole WIN 55,212-2. The K_i values for binding CB₁ and the peripheral cannabinoid (CB₂) receptor are 8.9 and 38 nM, respectively for a CB₁:CB₂ ratio of 0.23. JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 5-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018.

(1-Butyl-5-hydroxy-1H-indol-3-yl)-1-naphthalenylmethanone is a metabolite in human urine.