Uses
4-Ethylenedioxybutyllithium is a reagent used as a bis homoenolate equivalent for the production of aldehydes and lactones.
Preparation
4-Ethylenedioxybutyllithium can be obtained by treatment of a solution of chlorobutyraldehyde ethylene acetal (commercially available) in THF under inert gas with a solution of 2.4 equiv of Lithium Naphthalenide in THF at -78 °C for 7 h. Solutions are used directly.
storage
4-Ethylenedioxybutyllithium is purported to be stable at -78 °C.
