NSC 645827 is an inhibitor for NAD(P)H: quinone oxidoreductase 1 (NQO1) with an IC50 of 0.7 μM[1].
References
[1] Jianwen Wang, et al. Identification and structure-guided development of triazole urea-based selective antagonists of Arabidopsis karrikin signaling. Nat Commun. 2025 Jan 2;16(1):104. DOI:10.1038/s41467-024-54801-1 [2] Chee S M. Design, Synthesis and Biological Evaluation of the Novel Inhibitors of Enzymes NQO1 and NQO2[M]. The University of Manchester (United Kingdom), 2014.
