128-49-4

Surfak,Hoechst,US,1959

Calcium salt of Docusate, used for the treatment of constipation, acting as a laxative or stool softener.

Stool softener.

88 g of dioctyl sodium sulfosuccinate is first dissolved in 100 cc of isopropanol and 25 g of calcium chloride is dissolved in 50 cc of methanol. The solutions are then mixed and stirred for about 3 hours and then cooled with ice. The sodium chloride which precipitates in the cool mixture is removed by filtration and most of the alcohol is evaporated from the resulting filtrate with heat. The liquid remaining is poured into 88 cc of water, and the resulting precipitate washed with water until free of chloride ion. The washed calcium salt is then dried.

Surfak (Hoechst-Roussel).

Stool softener

Nonflammable