127697-58-9

Name	N-(4-Ethoxyphenylcarbonyl)-1,1,4,4-tetramethyltetralin-6-carboxamide
CAS	127697-58-9
Molecular Formula	C24H29NO3
MOL File	127697-58-9.mol

Synonyms

SRI-6409-94 N-(4-Ethoxyphenylcarbonyl)-1,1,4,4-tetramethyltetralin-6-carboxamide ethyl 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoate

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Chemical Properties

storage temp.	Store at -20°C
form	Solid
color	Light yellow to brown

Hazard Information

Uses

SRI 6409-94 is an orally active Ro 13-6298 analogue that is teratogenic. SRI 6409-94 serves as a molecular tool to study the effect of the three-dimensional configuration of retinol on teratogenic activity[1][2].

in vivo

SRI 6409-94 causes virgin female outbred syrian golden hamciasters to produce deformed offspring, in a dose-dependent manner^[1].
SRI 6409-94 leads to reductions in mean fetal body weight and in the numbers of ossified skeletal districts, significantly^[1].

storage

Store at -20°C

References

[1] Willhite CC, et al. Structure-activity relationships of retinoids in developmental toxicology. IV. Planar Cisoid conformational restriction. Toxicol Appl Pharmacol. 1990 Apr;103(2):324-44. DOI:10.1016/0041-008x(90)90233-k
[2] Willhite CC, et al. Structure-affinity relationships of retinoids with embryonic cellular retinoic acid-binding protein. Toxicol Appl Pharmacol. 1992 Jan;112(1):144-53. DOI:10.1016/0041-008x(92)90290-9

Supplier

Jinan Jiuli Biotechnology Co. , Ltd.

Telephone 15865264761

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList89365/0_EN.htm

Shanghai Yifei Biotechnology Co. , Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Zhejiang Huida Biotech Co., Ltd.

Telephone0571-89903022 18679456698

Websitehttps://www.huidacollection.cn

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