Description
KBR 2822 is an esterase inhibitor that causes exacerbation (promotion) of toxic and traumatic axonopathies.
Uses
KBR 2822 is an inhibitor of neurological target esterase (NTE) and has an inhibitory effect on AChE. KBR 2822 can aggravate neurological damage under certain conditions, but does not cause neurological disease when used alone in the absence of direct neurotoxicity or biochemical damage.
References
[1] Repeated low doses of O-(2-chloro-2, 3, 3 trifluorocyclobutyl) O-ethyl S-propyl phosphorothioate (KBR-2822) do not cause neuropathy in hens
