1263-79-2

Name	L-TETRANDRINE
CAS	1263-79-2
Molecular Formula	C38H42N2O6
MDL Number	MFCD00134987
Molecular Weight	622.75
MOL File	1263-79-2.mol

Synonyms

PHAENTHINE Pheanthine L-TETRANDRINE 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aR,16aR)-

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Chemical Properties

Melting point	210°
alpha	D20 -278° (chloroform)

Hazard Information

Uses

Pheanthine (Compound 2) is an antiplasmodial agent, that inhibits chloroquine-resistant Plasmodium falciparum K-1 (IC50 is 0.8 μM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC50 of 0.03 μM). Pheanthine exhibits low cytotoxicity in human lung fibrosblast (MRC-5, IC50 is 11.2 μM) and macrophages (PMM, IC50 is 8 μM)[1].

References

[1] Cimanga Kanyanga R., et al.,Isolation and structure elucidation of two antiprotozoal bisbenzylisoquinoline alkaloids from Triclisia gilletii stem bark. Phytochemistry Letters. 2018.

Spectrum Detail

L-TETRANDRINE(1263-79-2)¹HNMR

Supplier

Shaanxi Dideu Medichem Co. Ltd

Telephone +86-17392712779

Websitehttps://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-221/

Shanghai Yifei Biotechnology Co. , Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Shanghai Amole Biotechnology Co., Ltd.

Telephone13370042665 18916960931

Websitehttps://www.amole.com.cn/

GIHI CHEMICALS CO.,LIMITED

Telephone+86-571-86217390; +8618058761490

Websitehttps://www.gihichem.com/

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