125552-93-4

Name	MVT 101
CAS	125552-93-4
Molecular Formula	C35H67N11O8
Molecular Weight	769.99
MOL File	125552-93-4.mol

Synonyms

N-1465 MVT 101 Ac-L-Thr-L-Ile-L-Nleψ(CH2NH)-L-Nle-L-Gln-L-Arg-NH2 N-Ac-L-Thr-L-Ile-[(2S)-2-Amino*hexyl]-L-Nle-L-Gln-L-Arg-NH2 (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S,3R)-2-acetamido-3-hydroxybutanoyl]amino]-3-methylpentanoyl]amino]hexyl]amino]hexanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide

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Chemical Properties

density	1.31±0.1 g/cm3(Predicted)
pka	13.40±0.46(Predicted)
Sequence	Ac-Thr-Ile-{Nle}-{ψ(CH2-NH)}-{Nle}-Orn-Arg-NH2

Hazard Information

Description

Mvt 101 is a peptide inhibitor.

Uses

Mvt-101 is a hexapeptide-based inhibitor of HIV-1 protease. Mvt-101 is also reduced-peptide-bond inhibitor. Mvt-101 inhibits reproduction of the HIV virus by blocking protease action[1].

References

[1] Torbeev VY, et al. Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proc Natl Acad Sci USA. 2011 Dec 27;108(52):20982-7. DOI:10.1073/pnas.1111202108

Supplier

Hangzhou Peptidego Biotech Co.,Ltd.

Telephone0571-87213919 15967184799

Websitehttp://peptidego.com

Hangzhou Sinoda Pharmaceutical Technology Co. LTD

Telephone0571-87213919 17306812703

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList1355681/0_EN.htm

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

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