1250773-62-6

2,2-Difluoro-2-(2-methoxyphenyl)acetic Acid is primarily used to introduce benzylic difluoromethylene group to molecular scaffolds through radical decarboxylative reaction. The reaction begins with an oxidative decarboxylation with persulfate forming a difluorobenzyl radical that is stabilized by the benzene and fluorine groups. The addition is carried out by the attack of the radical species to the alkenes or imines.