1246820-09-6
| Name | Methylenedioxypyrovalerone-d8 Hydrochloride |
| CAS | 1246820-09-6 |
| EINECS(EC#) | 200-659-6 |
| Molecular Formula | C16H22ClNO3 |
| Molecular Weight | 311.804 |
| MOL File | 1246820-09-6.mol |
Synonyms
MDPV-d8
Oxygenate)
T Methanol
MDPV-D8 HCl
Trap Methanol
1000ug/mlEPTC
PereneysFluid
Methyl Red 0.1%
Acid Solution A
5% Chromic Acid
1000ug/ml2, 4DDD
1000ug/ml2, 4DDT
1000ug/mlHCHbeta
1000ug/ml2, 4DDE
1000ug/mlHCHdelta
1000ug/ml4, 4'DDT
1000ug/ml4, 4'DDE
1000ug/ml4, 4'DDD
Nitric Acid 5% w/v
500 μg/ml) in P&
Combined Acid Buffer
Ethanolamone 40% v/v
VOC Naphthalene Neat
Zinc Acetate 10% w/v
Methylene Blue, 0.1%
1000ug/mlTriademefon
1000ug/mlTrifuluralin
Kalling Etch Solution
Olsen’s Mixed Reagent
Holmium Oxide 4g/100ml
Sulphuric Acid 10% w/v
Diphenylcarbazone 0.1%
Sulphuric Acid 1:5 v/v
MS Soil Spike Standard
Van Gieson Stain 500ml
Tecator Mixed Indicator
Sodium Hydroxide 2% w/v
4% w/v Sodium Hydroxide
Sulphuric Acid 1:4 (v/v)
Formic Acid Solution 10%
Congo Red Indicator 0.1%
Hydrochloric Acid 10 g/l
Sulphuric Acid 33% (v/v)
Hydrochloric Acid 4% V/V
1000ug/mlPyrimiphosethyl
25% W/W Sodium Hydroxide
Hydrogen Peroxide 3% w/v
Hydrochloric Acid 10% w/v
Platinum-Cobalt Colour 80
Sodium Azide Solution 10%
1000ug/mlPyrimiphosmethyl
Ethanol 70% v/v Spray Top
Platinum-Cobalt Colour 50
Emameectin Benzoate, Neat
Hydrogen Peroxide 0.9% w/v
Redox Standard 468mV @25°C
Redox Standard 650mV @25°C
Redox Standard 475mV @25°C
Platinum-Cobalt Colour 500
Redox Standard 440mV @25°C
Redox Standard 600mV @25°C
Redox Standard 400mv @25°C
Indicator Methylene Blue 1%
Redox Standard 465mV @ 25°C
Copper Sulfate Solution 10%
Zinc Sulphate, ZnSO4, 6% w/v
Kroll Etchant Solution 500ml
Indicator Phenolphthalein 1%
0.25% Potassium Permanganate
Potassium Permanganate 5% w/v
Phosphate Buffer Solution 7.2
Piano Aromatics, 38 Compounds
Indicator Methyl Orange 0.04%
Piano Paraffins, 11 Compounds
Acetic Acid, CH3COOH, 20% v/v
Indicator Phenolphthalein 0.2%
MDPV-d8 (0.5mg/mL in Methanol)
Thymolphthalein Indicator 0.1%
VOC 35 Compound Mix, 2000ug/ml
Indicator Phenolphthalein 0.5%
Ammonia Solution (10% w/v NH3)
Pesticide Standard Aldrin Neat
Catechin Calibration Solutions
Indicator m-Cresol Purple, 0.4%
Lanthanum Compensating Solution
Indictaor Bromothymol Blue 0.4%
Chromotopic Acid Solution (CTA)
Barium Chloride Solution at 25%
Pesticide Standard 2,4-DDT Neat
Electrode Regeneration Solution
Pesticide Standard Dieldrin Neat
Hydrochloric Acid Solution (1+1)
Pesticide Standard 4,4'-DDT Neat
Arsenic Trioxide Standard 100ppm
Indicator Kovac's Indole Reagent
Piano Naphthalenes, 19 Compounds
Piano Isoparaffins, 35 Compounds
Density Standard 0.8482g/ml @40°C
Density Standard 0.7226g/ml @40°C
Density Standard 1.0265g/ml @25°C
Density Standard 1.0301g/ml @20°C
Density Standard 0.7033g/ml @50°C
Density Standard 0.7733g/ml @40°C
Density Standard 0.8387g/ml @50°C
Density Standard 0.9476g/ml @20°C
Density Standard 0.9815g/ml @80°C
Density Standard 0.8629g/ml @80°C
Density Standard 1.0073g/ml @50°C
Density Standard 0.6835g/ml @60°C
Density Standard 0.8292g/ml @60°C
Density Standard 0.6960g/ml @15°C
Density Standard 0.7076g/ml @60°C
Density Standard 0.8868g/ml @50°C
Density Standard 0.7220g/ml @80°C
Density Standard 0.7572g/ml @60°C
Density Standard 0.6919g/ml @20°C
Density Standard 0.7958g/ml @40°C
Density Standard 0.9695g/ml @60°C
Density Standard 0.7853g/ml @25°C
Density Standard 0.6752g/ml @40°C
Density Standard 0.7454g/ml @50°C
Density Standard 0.6791g/ml @50°C
Density Standard 0.7411g/ml @15°C
Density Standard 0.7376g/ml @60°C
Density Standard 0.6798g/ml @80°C
Density Standard 0.7683g/ml @20°C
Density Standard 0.8126g/ml @20°C
Density Standard 0.9098g/ml @20°C
Density Standard 0.7893g/ml @20°C
Density Standard 1.0337g/ml @15°C
Density Standard 0.7407g/ml @80°C
Density Standard 0.7788g/ml @60°C
Density Standard 0.6872g/ml @40°C
Density Standard 0.8027g/ml @60°C
Density Standard 0.9857g/ml @40°C
Density Standard 0.8945g/ml @40°C
Density Standard 0.9990g/ml @60°C
Density Standard 0.9135g/ml @15°C
Density Standard 0.6923g/ml @80°C
Density Standard 0.7033g/ml @20°C
Density Standard 0.8340g/ml @25°C
Density Standard 0.9245g/ml @50°C
Density Standard 0.7073g/ml @15°C
Density Standard 0.9520g/ml @80°C
Density Standard 0.9777g/ml @50°C
Density Standard 0.7223g/ml @25°C
Density Standard 0.8207g/ml @40°C
Density Standard 0.6993g/ml @25°C
Density Standard 0.8622g/ml @25°C
Density Standard 0.9006g/ml @80°C
Density Standard 1.0152g/ml @40°C
Density Standard 0.9514g/ml @15°C
Density Standard 0.6955g/ml @60°C
Density Standard 0.9166g/ml @60°C
Density Standard 0.6582g/ml @60°C
Density Standard 0.7298g/ml @15°C
Density Standard 0.7721g/ml @15°C
Density Standard 0.8384g/ml @20°C
Density Standard 0.9438g/ml @25°C
Density Standard 0.7109g/ml @40°C
Density Standard 0.7645g/ml @25°C
Density Standard 1.0040g/ml @15°C
Density Standard 0.6661g/ml @80°C
Density Standard 0.7374g/ml @20°C
Density Standard 0.8118g/ml @50°C
Density Standard 0.9969g/ml @25°C
Density Standard 0.8168g/ml @15°C
Density Standard 1.0005g/ml @20°C
Density Standard 0.7531g/ml @40°C
Density Standard 0.6917g/ml @50°C
Density Standard 0.6878g/ml @25°C
Density Standard 0.7184g/ml @15°C
Density Standard 0.8084g/ml @25°C
Density Standard 0.8715g/ml @15°C
Density Standard 0.8098g/ml @80°C
Density Standard 0.7933g/ml @15°C
Density Standard 0.7151g/ml @50°C
Density Standard 0.8790g/ml @60°C
Density Standard 0.9323g/ml @40°C
Density Standard 0.7614g/ml @80°C
Density Standard 0.7873g/ml @50°C
Density Standard 0.9060g/ml @25°C
Density Standard 0.6997g/ml @40°C
Density Standard 0.7111g/ml @25°C
Density Standard 0.7653g/ml @50°C
Density Standard 0.7337g/ml @25°C
Density Standard 0.6668g/ml @50°C
Density Standard 0.6708g/ml @60°C
Density Standard 0.7844g/ml @80°C
Density Standard 0.8428g/ml @15°C
Density Standard 1.0302g/ml @80°C
Density Standard 0.6538g/ml @80°C
Density Standard 0.7148g/ml @20°C
Density Standard 0.7261g/ml @20°C
Density Standard 0.8668g/ml @20°C
Bromocresol Green Indicator, 0.04%
3,4-Methylenedioxy Pyrovalerone-d8
Sodium Hydroxide 30% w/w (40% w/v)
Hydrochloric Acid 15% in 1000L IBC
Pesticide Standard Heptachlor Neat
TA Indicator - Phenolphthalein Free
ICP Standard Iron 100ppm in 2% HNO3
10% Stannous Chloride in 10% HCl v/v
Pesticide Standard Endosulfan I Neat
Potassium Dichromate Reagent, 0.267N
Indicator Solution for Mixed Sulphur
ICP Standard Lead 10μg/ml in 2% HNO3
COD Vials - Measuring Range 0-150mg/L
Ammonia Solution 25%- Technical Grade
ICP Standard Zinc 2μg/ml in 2-5% HNO3
DensityPremium Standard0.8790g/ml@60°C
DensityPremium Standard0.9245g/ml@50°C
DensityPremium Standard0.6538g/ml@80°C
DensityPremium Standard0.6798g/ml@80°C
DensityPremium Standard0.6955g/ml@60°C
DensityPremium Standard0.7893g/ml@20°C
DensityPremium Standard0.8126g/ml@20°C
DensityPremium Standard1.0562g/ml@50°C
DensityPremium Standard0.6835g/ml@60°C
DensityPremium Standard0.8292g/ml@60°C
DensityPremium Standard1.0005g/ml@20°C
DensityPremium Standard0.7454g/ml@50°C
DensityPremium Standard0.7298g/ml@15°C
Chemical Properties
| Melting point | 227-229?C |
| Fp | 9℃ |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | DMF: 0.25 mg/ml; DMSO: 0.1 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml |
| form | A crystalline solid |
| Stability: | Hygroscopic |
| Major Application | pharmaceutical (small molecule) |
Safety Data
| Hazard Codes | F,T |
| Risk Statements | |
| Safety Statements | |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 1 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Eye Irrit. 2 Flam. Liq. 2 |
Hazard Information
Description
3,4-Methylenedioxy Pyrovalerone-
Chemical Properties
White Solid
Uses
Labelled Methylenedioxypyrovalerone (M304080) as a central nervous system
Uses
Labelled Methylenedioxypyrovalerone (MDPV; Cat. # M304080) as a central nervous system
References
[1] CATHERINE HéRON Jean J B Jean Costentin. Evidence that pure uptake inhibitors including cocaine interact slowly with the dopamine neuronal carrier[J]. European journal of pharmacology, 1994, 264 3: Pages 391-398. DOI: 10.1016/0014-2999(94)00502-8
[2] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[3] FOLKER WESTPHAL . Mass and NMR spectroscopic characterization of 3,4-methylenedioxypyrovalerone: A designer drug with α-pyrrolidinophenone structure[J]. Forensic science international, 2009, 190 1: Pages 1-8. DOI: 10.1016/j.forsciint.2009.05.001
[4] MARKUS R. MEYER. Studies on the metabolism of the α-pyrrolidinophenone designer drug methylenedioxy-pyrovalerone (MDPV) in rat and human urine and human liver microsomes using GC–MS and LC–high-resolution MS and its detectability in urine by GC–MS[J]. Journal of Mass Spectrometry, 2010, 45 12: 1426-1442. DOI: 10.1002/jms.1859
[5] KINGA FARKAS. [Clinical characteristics of 5 hospitalized 3,4-methylenedioxypyrovalerone (MDPV) users].[J]. Psychiatria Hungarica, 2013, 28 4: 431-439.
[6] SABINA STRANO-ROSSI. Toxicological determination and in vitro metabolism of the designer drug methylenedioxypyrovalerone (MPDV) by gas chromatography/mass spectrometry and liquid chromatography/quadrupole time-of-flight mass spectrometry[J]. Rapid Communications in Mass Spectrometry, 2010, 24 18: 2706-2714. DOI: 10.1002/rcm.4692
[2] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[3] FOLKER WESTPHAL . Mass and NMR spectroscopic characterization of 3,4-methylenedioxypyrovalerone: A designer drug with α-pyrrolidinophenone structure[J]. Forensic science international, 2009, 190 1: Pages 1-8. DOI: 10.1016/j.forsciint.2009.05.001
[4] MARKUS R. MEYER. Studies on the metabolism of the α-pyrrolidinophenone designer drug methylenedioxy-pyrovalerone (MDPV) in rat and human urine and human liver microsomes using GC–MS and LC–high-resolution MS and its detectability in urine by GC–MS[J]. Journal of Mass Spectrometry, 2010, 45 12: 1426-1442. DOI: 10.1002/jms.1859
[5] KINGA FARKAS. [Clinical characteristics of 5 hospitalized 3,4-methylenedioxypyrovalerone (MDPV) users].[J]. Psychiatria Hungarica, 2013, 28 4: 431-439.
[6] SABINA STRANO-ROSSI. Toxicological determination and in vitro metabolism of the designer drug methylenedioxypyrovalerone (MPDV) by gas chromatography/mass spectrometry and liquid chromatography/quadrupole time-of-flight mass spectrometry[J]. Rapid Communications in Mass Spectrometry, 2010, 24 18: 2706-2714. DOI: 10.1002/rcm.4692
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