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C16 Ceramide-1-phosphate (C16 C1P) is one of the main forms of C1P found in cells.¹ It is created by phosphorylation of C16 ceramide by ceramide kinase. C16 C1P activates cytosolic phospholipase A₂α (PLA₂α) and stimulates the release of arachidonic acid in A549 cells.²

1. Lamour, N.F., Stahelin, R.V., Wijesinghe, D.S., et al. Ceramide kinase uses ceramide provided by ceramide transport protein: Localization to organelles of eicosanoid synthesis J. Lipid Res. 48(6),1293-1304(2007).
2. Wijesinghe, D.S., Subramanian, P., Lamour, N.F., et al. Chain length specificity for activation of cPLA2alpha by C1P: Use of the dodecane delivery system to determine lipid-specific effects J. Lipid Res. 50(10),1986-1995(2009).