1240390-32-2

1240390-30-0

1240390-32-2

Step 4: (3S,4S)-3-((S)-1-phenylethylamino)tetrahydro-2H-pyran-4-ol (1.47 g, 6.65 mmol) was dissolved in ethanol (25 mL) and palladium/carbon hydroxide (Pd(OH)2/C, 200 mg) was added. The mixture was placed in a Parr shaker and the reaction was shaken for 15 h under hydrogen (30 psi) atmosphere. After completion of the reaction, the Pd(OH)2/C was removed by filtration and the filtrate was concentrated to give (3S,4S)-3-aminotetrahydro-2H-pyran-4-ol (600 mg).