121995-36-6

SQ 30774 is a representatives of a novel class of renin inhibitors, the imidazole alcohols.

SQ 30774 is a renin (renin) inhibitor. SQ 30774 has potent in vitro inhibitory effects in primates but not in rats, pigs, or dogs. And imidazolinol renin inhibitors also inhibit PRA and reduce arterial blood pressure in vivo[1].

[1] Pharmacology of novel imidazole alcohol inhibitors of primate renin