1216563-60-8

2-(4-Fluorophenyl)propan-2-amine Hydrochloride acts as a reagent in the discovery of a selective TRPM8 antagonist with clinical efficacy in cold-related pain. Preparation and SAR of piperazinyl-amino-thiophenylcyclohexylmethanone derivatives as antagonists of the G protein-coupled receptor NPBWR1.