120958-90-9

Dalcotidine (KU-1257) is an orally active and competitive histamine H2 receptor antagonist. Dalcotidine promotes the healing of chronic ulcers and inhibits gastric acid secretion[1][2].

ChEBI: Dalcotidine is a member of piperidines.

[1] Sekiguchi H, et al. Healing-promoting action of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]urea with dual action on chronic gastric and duodenal ulcers induced by acetic acid in rats. Arzneimittelforschung. 1993;43(2):139-143. PMID:8096134
[2] Sekiguchi H, et al. Effects of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl] urea with potent gastric mucosal protective activity on acute gastric lesions and duodenal ulcers in rats. Arzneimittelforschung. 1993;43(2):134-138. PMID:8096133